PUBLICATIONS

 

Mitochondrial dysfunction in glaucoma: understanding genetic influences.

Lascaratos G, Garway-Heath DF, Willoughby CE, Chau KY, Schapira AH.

Mitochondrion. 2012 Mar;12(2):202-12.

 

Resistance to the most common optic neuropathy is associated with systemic mitochondrial efficiency.

Lascaratos G, Chau KY, Zhu H, Gkotsi D, King R, Gout I, Kamal D, Luthert PJ, Schapira AHV, Garway-Heath DF.

Neurobiol Dis. 2015 Oct;82:78-85.

 

The United Kingdom Glaucoma Treatment Study: a multicenter, randomized, double-masked, placebo-controlled trial: baseline characteristics.

Lascaratos G, Garway-Heath DF, Burton R, Bunce C, Xing W, Crabb DP, Russell RA, Shah A; United Kingdom Glaucoma Treatment Study Group.

Ophthalmology. 2013 Dec;120(12):2540-2545.

 

Latanoprost for open-angle glaucoma (UKGTS): a randomised, multicentre, placebo-controlled trial.

Garway-Heath DF, Crabb DP, Bunce C, Lascaratos G, Amalfitano F, Anand N, Azuara-Blanco A, Bourne RR, Broadway DC, Cunliffe IA, Diamond JP, Fraser SG, Ho TA, Martin KR, McNaught AI, Negi A, Patel K, Russell RA, Shah A, Spry PG, Suzuki K, White ET, Wormald RP, Xing W, Zeyen TG.

Lancet. 2015 Apr 4;385(9975):1295-304.

 

Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error.

Tedja MS, Wojciechowski R, Hysi PG, Eriksson N, Furlotte NA, Verhoeven VJM, Iglesias AI, Meester-Smoor MA, Tompson SW, Fan Q, Khawaja AP, Cheng CY, Höhn R, Yamashiro K, Wenocur A, Grazal C, Haller T, Metspalu A, Wedenoja J, Jonas JB, Wang YX, Xie J, Mitchell P, Foster PJ, Klein BEK, Klein R, Paterson AD, Hosseini SM, Shah RL, Williams C, Teo YY, Tham YC, Gupta P, Zhao W, Shi Y, Saw WY, Tai ES, Sim XL, Huffman JE, Polašek O, Hayward C, Bencic G, Rudan I, Wilson JF; CREAM Consortium; 23andMe Research Team; UK Biobank Eye and Vision Consortium, Joshi PK, Tsujikawa A, Matsuda F, Whisenhunt KN, Zeller T, van der Spek PJ, Haak R, Meijers-Heijboer H, van Leeuwen EM, Iyengar SK, Lass JH, Hofman A, Rivadeneira F, Uitterlinden AG, Vingerling JR, Lehtimäki T, Raitakari OT, Biino G, Concas MP, Schwantes-An TH, Igo RP Jr, Cuellar-Partida G, Martin NG, Craig JE, Gharahkhani P, Williams KM, Nag A, Rahi JS, Cumberland PM, Delcourt C, Bellenguez C, Ried JS, Bergen AA, Meitinger T, Gieger C, Wong TY, Hewitt AW, Mackey DA, Simpson CL, Pfeiffer N, Pärssinen O, Baird PN, Vitart V, Amin N, van Duijn CM, Bailey-Wilson JE, Young TL, Saw SM, Stambolian D, MacGregor S, Guggenheim JA, Tung JY, Hammond CJ, Klaver CCW.

Nat Genet. 2018 Jun;50(6):834-848

 

Systemic PTEN-Akt1-mTOR pathway activity in patients with normal tension glaucoma and ocular hypertension: A case series.

Lascaratos G, Chau KY, Zhu H, Gkotsi D, Kamal D, Gout I, Luthert PJ, Schapira AHV, Garway-Heath DF.

Mitochondrion. 2017 Sep;36:96-102.

 

The United Kingdom Glaucoma Treatment Study: a multicenter, randomized, placebo-controlled clinical trial: design and methodology.

Garway-Heath DF, Lascaratos G, Bunce C, Crabb DP, Russell RA, Shah A; United Kingdom Glaucoma Treatment Study Investigators.

Ophthalmology. 2013 Jan;120(1):68-76.

 

A hypothesis to suggest that light is a risk factor in glaucoma and the mitochondrial optic neuropathies.

Osborne NN, Lascaratos G, Bron AJ, Chidlow G, Wood JP.

Br J Ophthalmol. 2006 Feb;90(2):237-41. Review.

 

Visible light affects mitochondrial function and induces neuronal death in retinal cell cultures.

Lascaratos G, Ji D, Wood JP, Osborne NN.

Vision Res. 2007 Apr;47(9):1191-201. Epub 2007 Feb 16.

 

Are Patient Self-Reported Outcome Measures Sensitive Enough to Be Used as End Points in Clinical Trials?: Evidence from the United Kingdom Glaucoma Treatment Study.

Jones L, Garway-Heath DF, Azuara-Blanco A, Crabb DP; United Kingdom Glaucoma Treatment Study Investigators.

Ophthalmology. 2019 May;126(5):682-689.

 

Cohort profile: design and methods in the eye and vision consortium of UK Biobank.

Chua SYL, Thomas D, Allen N, Lotery A, Desai P, Patel P, Muthy Z, Sudlow C, Peto T, Khaw PT, Foster PJ; UK Biobank Eye & Vision Consortium.

BMJ Open. 2019 Feb 21;9(2):e025077.

 

Advanced cocaine-related necrotising sinusitis presenting with restrictive ophthalmolplegia.

Lascaratos G, McHugh J, McCarthy K, Bunting H.

Orbit. 2016 Jun;35(3):164-6.

 

Associations with Intraocular Pressure in a Large Cohort: Results from the UK Biobank.

Chan MP, Grossi CM, Khawaja AP, Yip JL, Khaw KT, Patel PJ, Khaw PT, Morgan JE, Vernon SA, Foster PJ; UK Biobank Eye and Vision Consortium.

Ophthalmology. 2016 Apr;123(4):771-82.

 

Spectral-Domain Optical Coherence Tomography Imaging in 67 321 Adults: Associations with Macular Thickness in the UK Biobank Study.

Patel PJ, Foster PJ, Grossi CM, Keane PA, Ko F, Lotery A, Peto T, Reisman CA, Strouthidis NG, Yang Q; UK Biobank Eyes and Vision Consortium.

Ophthalmology. 2016 Apr;123(4):829-40.

 

Role of Educational Exposure in the Association Between Myopia and Birth Order.

Guggenheim JA, Williams C; UK Biobank Eye and Vision Consortium.

JAMA Ophthalmol. 2015 Dec;133(12):1408-14.

 

Frequency and Distribution of Refractive Error in Adult Life: Methodology and Findings of the UK Biobank Study.

Cumberland PM, Bao Y, Hysi PG, Foster PJ, Hammond CJ, Rahi JS; UK Biobank Eyes & Vision Consortium.

PLoS One. 2015 Oct 2;10(10):e0139780.

 

Latanoprost for glaucoma: primum non nocere – Authors’ reply.

Garway-Heath DF, Bunce C, Broadway DC, Martin KR, Lascaratos G, Wormald RP.

Lancet. 2015 Aug 15;386(9994):652.

 

Measures of socioeconomic status and self-reported glaucoma in the U.K. Biobank cohort.

Shweikh Y, Ko F, Chan MP, Patel PJ, Muthy Z, Khaw PT, Yip J, Strouthidis N, Foster PJ; UK Biobank Eye and Vision Consortium.

Eye (Lond). 2015 Oct;29(10):1360-7.

 

Corneal Cross-linking to Halt the Progression of Keratoconus and Corneal Ectasia: Seven-Year Follow-up.

O’Brart DP, Patel P, Lascaratos G, Wagh VK, Tam C, Lee J, O’Brart NA.

Am J Ophthalmol. 2015 Dec;160(6):1154-63.

 

Evaluation of the effect of intravitreal ranibizumab injections in patients with neovascular age related macular degeneration on retinal nerve fiber layer thickness using optical coherence tomography.

El-Ashry MF, Lascaratos G, Dhillon B.

Clin Ophthalmol. 2015 Jul 13;9:1269-74.

 

Suitability of UK Biobank Retinal Images for Automatic Analysis of Morphometric Properties of the Vasculature.

MacGillivray TJ, Cameron JR, Zhang Q, El-Medany A, Mulholland C, Sheng Z, Dhillon B, Doubal FN, Foster PJ, Trucco E, Sudlow C; UK Biobank Eye and Vision Consortium.

PLoS One. 2015 May 22;10(5):e0127914.

 

Type 2 diabetes mellitus and microvascular complications 1 year after Roux-en-Y gastric bypass: a case-control study.

Miras AD, Chuah LL, Khalil N, Nicotra A, Vusirikala A, Baqai N, Graham C, Ravindra S, Lascaratos G, Oliver N, le Roux CW.

Diabetologia. 2015 Jul;58(7):1443-7.

 

Association between rate of binocular visual field change and vision-related quality of life: novel finding or spurious association?

Writing Committee for the European Glaucoma Panel, Jóhannesson G, Abouzeid H, Somner JE.

JAMA Ophthalmol. 2014 Jun;132(6):784-5.

 

Longitudinal study of iris concavity, corneal biomechanics, and correlations to ocular biometry in a cohort of 10- to 12-year-old UK schoolboys: 2-year follow-up data.

Shah A, Lascaratos G, Garway-Heath DF, Foster PJ, Barton K.

Invest Ophthalmol Vis Sci. 2014 Jun 10;55(7):4645-50.

 

Recharging mitochondrial batteries in old eyes. Near infra-red increases ATP.

Gkotsi D, Begum R, Salt T, Lascaratos G, Hogg C, Chau KY, Schapira AH, Jeffery G.

Exp Eye Res. 2014 May;122:50-3.

 

Corrigendum to “Retinal thinning in Gaucher disease patients and carriers: Results of a pilot study” [Mol. Genet. Metab. 109 (2013) 221-223].

McNeill A, Roberti G, Lascaratos G, Hughes D, Mehta A, Garway-Heath DF, Schapira AHV.

Mol Genet Metab. 2014 Mar;111(3):408

 

Retinal nerve fiber layer thickness and cognitive ability in older people: the Lothian Birth Cohort 1936 study.

Laude A, Lascaratos G, Henderson RD, Starr JM, Deary IJ, Dhillon B.

BMC Ophthalmol. 2013 Jul 3;13:28.

 

Retinal thinning in Gaucher disease patients and carriers: results of a pilot study.

McNeill A, Roberti G, Lascaratos G, Hughes D, Mehta A, Garway-Heath DF, Schapira AH.

Mol Genet Metab. 2013 Jun;109(2):221-3.

 

Alcoholic liver disease and bilateral multifocal central serous retinopathy: a case report.

Gkotsi D, Gupta M, Lascaratos G, Syrogiannis A, Dhillon B.

J Med Case Rep. 2013 Feb 13;7:43.

 

The genetics of pigment dispersion syndrome and pigmentary glaucoma.

Lascaratos G, Shah A, Garway-Heath DF.

Surv Ophthalmol. 2013 Mar-Apr;58(2):164-75.

 

Bariatric surgery does not exacerbate and may be beneficial for the microvascular complications of type 2 diabetes.

Miras AD, Chuah LL, Lascaratos G, Faruq S, Mohite AA, Shah PR, Gill M, Jackson SN, Johnston DG, Olbers T, le Roux CW.

Diabetes Care. 2012 Dec;35(12):e81.

 

Accelerated diabetic retinopathy and late human immunodeficiency virus diagnosis.

Gupta M, Syrogiannis A, Lascaratos G, Laude A, Dhillon B.

Retin Cases Brief Rep. 2012 Spring;6(2):139-41.

 

A rare case of zolendronate infusion complication leading to glaucoma filtration surgery.

Khan A, Lascaratos G, Rane-Malcolm T, Sanders R.

Clin Ophthalmol. 2011;5:1147-9.

 

Adams-Oliver syndrome associated with bilateral anterior polar cataracts and optic disk drusen.

Lascaratos G, Lam WW, Newman WD, MacRae M.

J AAPOS. 2011 Jun;15(3):299-301.

 

Nystagmus and reduced visual acuity secondary to drug exposure in utero: long-term follow-up.

Gupta M, Mulvihill AO, Lascaratos G, Fleck BW, George ND.

J Pediatr Ophthalmol Strabismus. 2012 Jan-Feb;49(1):58-63.

 

Myofibroma of the conjunctiva invading the cornea in infancy.

Lascaratos G, Gupta M, Bridges L, MacRae M.

J Pediatr Ophthalmol Strabismus. 2010 May 21;47 Online:e1-3.

 

Outcome of phacoemulsification in previously vitrectomized myopic eyes with axial length greater than 26 mm.

Gupta M, Lascaratos G, Syrogiannis A, Verma S.

Eur J Ophthalmol. 2011 Jul-Aug;21(4):379-84.

 

The role of retinal regulation of sleep in health and disease.

Schmoll C, Lascaratos G, Dhillon B, Skene D, Riha RL.

Sleep Med Rev. 2011 Apr;15(2):107-13.

 

Pearls & Oy-sters: spontaneous venous pulsation and its role in differentiating papilledema from pseudopapilledema.

Lascaratos G, Ahmed S, Madill SA.

Neurology. 2010 Sep 28;75(13):e53-4.

 

Intravitreal therapy for neovascular age-related macular degeneration and inter-individual variations in vitreous pharmacokinetics.

Laude A, Tan LE, Wilson CG, Lascaratos G, Elashry M, Aslam T, Patton N, Dhillon B.

Prog Retin Eye Res. 2010 Nov;29(6):466-75.

 

Isolated bilateral trigeminal neuropathy in sarcoidosis presenting with neurotrophic corneal ulcers.

Gupta M, Lascaratos G, Syrogiannis A, Esakowitz L.

Ophthalmol Eye Dis. 2010 Nov 30;2:69-73.

 

Perceived color of hallucinations in the Charles Bonnet Syndrome is related to residual color contrast sensitivity.

Madill SA, Lascaratos G, Arden GB, ffytche DH.

J Neuroophthalmol. 2009 Sep;29(3):192-6

 

Intraocular pressures after ketamine and sevoflurane in children with glaucoma undergoing examination under anaesthesia.

Jones L, Sung V, Lascaratos G, Nagi H, Holder R.

Br J Ophthalmol. 2010 Jan;94(1):33-5.

 

The influence of visible light exposure on cultured RGC-5 cells.

Wood JP, Lascaratos G, Bron AJ, Osborne NN.

Mol Vis. 2007 Feb 11;14:334-44.

 

The influence of visible light exposure on cultured RGC-5 cells.

Wood JP, Lascaratos G, Bron AJ, Osborne NN.

Mol Vis. 2007 Feb 11;14:334-44.

 

The ophthalmic wound of Philip II of Macedonia (360-336 BCE).

Lascaratos J, Lascaratos G, Kalantzis G.

Surv Ophthalmol. 2004 Mar-Apr;49(2):256-61.